American Board of Orthodontics (ABO) Practice Exam 2026 - Free Orthodontics Practice Questions and Study Guide

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What is the function of the clear zone in osteoclasts?

Increase bone mineralization

Facilitate lymphatic drainage

Seal off the resorption area

The clear zone in osteoclasts serves a critical role in the process of bone resorption. It acts as a ring-like structure that forms a tight seal around the area of bone that is being actively resorbed. By creating this sealed-off area, the clear zone allows the osteoclast to create a microenvironment conducive to bone breakdown, enhancing the effectiveness of the resorption process.

In this localized environment, the osteoclast can concentrate the release of acids and enzymes necessary for dissolving the mineral component of bone and breaking down the organic matrix. This function is essential for the efficient removal of bone tissue, facilitating the balance of bone formation and resorption, which is crucial for maintaining healthy bone metabolism. The presence of the clear zone thus directly supports the osteoclast's primary role in bone remodeling.

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Maintain cellular energy

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